Skip to content

Comment · Tue, January 14, 2014

Another MDMA re-dose/redose question [first and second time MDMA experience inside]

Original post in this thread

YouKnowNothingJohn · 8 points

Although having read plenty of information on reddit and MDMA forums/sites, I still have a couple of questions regarding the dosing and specifically re-dosing of MDMA. I am familiar with the reasons behind the advise to only re-dose once shortly into your roll. Let me first give you some background.

Warning, long post, skip to bottom if not interested

*****
##Background

Our group uses MDMA at home and on festivals, the usage is quite low since we strictly keep three or more months between each use. No crazy amounts of MDMA are taken either. Living in the country we live in, we fortunately have access to high quality xtc pills and government testing facilities. At the moment we have some 100% clean pills with 205mg of pure MDMA inside.

For me personally I have used MDMA two times, both at festivals, and we will do a home session within one month's time. The last time we used I had already purchased some vitamin C and magnesium supplements to try to make the roll a bit safer.

Everyone in the group was into the idea of doing MDMA as safe as we could. I started reading a lot on how MDMA works and made my own supplement list based on different sources but mainly posts by Miste…

What they were answering

YouKnowNothingJohn · 1 points

Hi Mister! Thanks for the reply. I am aware of the role of supplements, I do not consider them capable of removing every negative effect! I would however expect them to lower the risk of damage due to re-dosing.

To be clear, we haven't tried the full regiment yet, this is planned for the next home session as a try out. We have just ordered all of the supplements yesterday.

Regarding the differences between the two events, I think there were some. The first event we started at five o'clock, so quite an empty stomach although one guy had a slice of pizza even before we dropped the first dose. I ordered a portion of fries before the second drop.

The second event we started around 3 o'clock and if I remember correctly we all had a small(!) Burger King meal around 1:30 I guess. Before we left home we took some Vitamin C pills (3x240mg I think) but I don't think the impact on acidity would be that big. Maybe the drink of Coke at the Burger King made our stomach more acid.

Then of course, there are the differences in dosages and setting as described in the OP.

Have you experienced MDMA like I have described it for my second time rolling? We were with six friends and simply put: everybody LOVED the slow come up and the day just couldn't have been any better. I can imagine we might want to try to consciously recreate that slow effect.

Basically it boils down to this: I talked abo…

u/MisterYouAreSoDumb

Yes, I have experienced that. The slow comeup is most likely due to absorption issues in your GI tract, and possibly transport issues across the BBB. If you wanted to recreate that effect, you could make a time release MDMA capsule. That would probably be the easiest and most reliable way to accomplish that effect. Trying to accurately modify your body's pH is going to be hard, and vary from person to person. Creating an enteric coated capsule is relatively straightforward.

Other MYASD lines in this thread

Related in the archive

Commentr/NootropicsDepotMar 11, 2025

Why is your enteric NMN 4x stronger subjectively than double wood?

We are the only real enteric delivery NMN on the market, and that makes a big difference in your body's ability to absorb it. There is a reason we set our dose where we did, and that was due to a lot of testing on NMN do

14COADosingNMN
Commentr/NootropicsDepotApr 10, 2024

Question about Microbial Test Standards

WTF is that guy on about?!? We use the limits set by both USP and the AHPA. https://ahpa.gomembers.com/Portals/0/PDFs/Policies/Guidance-Policies/Microbiology___Mycotoxin_Guidance.pdf The limit is 10,000 CFU (10^4) for

10BacopaL-theanineMagnesiumCOA
Commentr/NootropicsDepotMar 4, 2022

⚠️ NEW PRODUCTS ALERT | NMN 250mg Capsules, NMN Powder, Sabroxy 500mg Tablets, L-Pyroglutamic Acid Capsules, L-Pyroglutamic Acid Powder, & Super Critical Holy Basil Solution ⚠️

Replying to solothesensei · A question on the NMN powder for the ND team - as I understood it, the enteric coating is critical for transporting NMN to the intestine for absorption. Since the powder is set

It's not that simple, as people's GI systems are complex. However, that was the dosing equivalent we went with.

9COADosingNMN
Commentr/NootropicsDepotJan 30, 2022

NMN Powder

Replying to Sherlockian_Holmes · Wonderful. Thank you for the great news! Are you looking into Resveratrol as well? I've looked at bioavailability data for NMN and NR, I am not finding much good information, as i

https://europepmc.org/articles/pmc6530925?pdf=render You can see from that study that NMN has its own transporter located in the small intestine. This transporter, called Slc12a8, is a nicotinamide mononucleotide specif

9COADosingNMNResveratrol
Commentr/NootropicsDepotJun 21, 2020

Capsule request: Carnosine and Milk Thistle

We have berberine and milk thistle coated tablets in production now. We are also about to do standalone milk thistle/silymarin capsules. The issue is that everyone is saying their milk thistle is 80% silymarins, but it i

9COADosingMilk thistle
Commentr/NootropicsDepotOct 28, 2020

Tongkat Ali Nausea

Replying to Majalisk · Yeah, I definitely would stress the coating for the berberine since that truly is vile. Try oblate discs sometime. I ignored them for years and now love them after finally giving

Yeah, one of my employees turned me on to oblate disks years ago. They are common in Japan. It's a good solution for dosing powders. I've thought about offering them on the site.

8Tongkat aliCOADosing