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Cyclobenzaprine (tricyclic antidepressant marketed as muscle relaxer)
Replying to unbutter_robot · /u/MisterYouAreSoDumb calling upon the nootropics king/queen for advice in return i offer the law of surprise
Damn, that doesn't sound fun! That's going to be a difficult case. It should certainly have resolved after 10 days. It seems like strange reactions can happen to that drug, though. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669814/
Another MDMA re-dose/redose question [first and second time MDMA experience inside]
Replying to YouKnowNothingJohn · I very much appreciate your detailed explanations! If you wouldn't mind I'd like to ask a few more questions regarding the details behind the neurotoxic risk involved with taking M…
HHA itself is not toxic. It has to conjugate with gluthatione before it can pass the blood brain barrier and cause oxidative damage to your neurons. So it's kind of ironic that your body's natural defense system is needed to actually create the very thing that damages it. HHM is…
Another MDMA re-dose/redose question [first and second time MDMA experience inside]
Replying to YouKnowNothingJohn · Makes sense. I think for the next home session we will make a quick planning how much to take at what times. Also making sure that we don't eat a fatty dinner and have too much aci…
>If I am correct, the way the MDMA is delayed should have no effect on the increased neurotoxicity right? Well that is complicated, since MDMA's pharmacodynamics are complex. If the Cmax is lower, but the AUC is the same, then some aspects of the neurotoxicity will be lower. Name…
Another MDMA re-dose/redose question [first and second time MDMA experience inside]
Replying to YouKnowNothingJohn · Hi Mister! Thanks for the reply. I am aware of the role of supplements, I do not consider them capable of removing every negative effect! I would however expect them to lower the r…
Yes, I have experienced that. The slow comeup is most likely due to absorption issues in your GI tract, and possibly transport issues across the BBB. If you wanted to recreate that effect, you could make a time release MDMA capsule. That would probably be the easiest and most rel…
Another MDMA re-dose/redose question [first and second time MDMA experience inside]
My supplementation is not going to do anything for down-regulation, or desensitization. It's merely there to protect you from the harmful effects of the reactive species that get created, and to slow the process creating them. Don't go chasing the feeling. The more times you re-d…
MDA vs MDMA
Replying to Borax · You normally some good input on MDA :)
Ohh, ok! Haha MDA is definitely more of a pushy drug. Some people love it. 6-APB was actually more like MDA than it was MDMA. You trade the lovey feelings of MDMA for more psychedelic and euphoric feelings. MDA is a more potent dopamine releaser than MDMA, and that definitely add…
MDA vs MDMA
Replying to Borax · ^^^^/u/misteryouaresodumb MDA Is much easier to manufacture so based on that alone, I think if it were more enjoyable then its popularity would have surged since 1988, yet it hasn…
Yes Borax, you rang?