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Comment · Mon, November 4, 2013 · Ceretropic

Fairly disappointed with racetams.

Original post in this thread

NeilDeSnowden · 20 points

I tried Piracetam about a year ago, and I really did think it had fairly significant positive effects. But I tried it again in the last few days (from nootropics depot, so probably legit) and all it's done is make me tired with barely noticeable positive effects.

I also got some Aniracetam from the same place and it has about the same effects.

Not much point to this post except to add to the data available from users.

Along with all the posts, on here and other forums, about people experiencing brain fog long term, I really don't think these racetams are worth using. Not for the barely better than placebo effect they have.

What are some more promising alternatives? I know about Memantine and also Modafinil, but both also seem to have very little study and/or severe side-effects, like Stevens-Johnson syndrome (nope nope nope).

I've also tried Alpha Brain, so probably Vinpocetine and Huperzine A are the most significant things in there, and it did have an effect, but I found it very, very hard to concentrate.

What they were answering

iGotMyPhdInThis · 4 points

Sorry to have to disagree with you here:

Age/Sex Event Time to onset Biopsy Case Summary
49/F TEN 20 days Yes A patient who initiated recommended doses of modafinil for a sleep disorder was hospitalized on day 20 in the burn unit for a severe life-threatening exfoliating skin reaction. Although the patient had an extensive medication history, modafinil was the primary suspect drug because it was the last agent added to the drug regimen. The patient improved, despite the continuation of several concomitant medications, some of which, such as celecoxib and propranolol, have labeled warnings for TEN.
42/F SJS/TEN 14 days Yes A patient received concomitant medications since 2005 before adding modafinil for a sleep disorder in 2006. The patient's extensive body rash (30% BSA) with the confirmation of biopsy led to the final SJS/TEN diagnosis.
17/F SJS 45 days Not reported A patient received both modafinil 300 mg daily for the treatment of attention deficit disorder (ADD) and Lamictal (labeled warnings for SJS) for about 2 months. The patient was hospitalized over 5 days for SJS. Both drugs were discontinued. One to 2 months later, the patient received one dose of modafinil 50 mg and developed a skin rash that also involved the patient's mouth. Modafinil was discontinued.
27/F SJS/EM 5 days Yes A patient had received 5 days of modafinil when she presented to the hospital w…

u/MisterYouAreSoDumb · Ceretropic

Wow, good to know. I had not seen those. Where did you find those cases?

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