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Comment · Wed, August 14, 2013 · Ceretropic

Bacopa and Lexapro

What they were answering

Direct reply to the original post in this thread.

u/MisterYouAreSoDumb · Ceretropic

Bacopa up-regulates tryptophan hydroxylase, which helps the body produce more serotonin. However, it's not going to cause a release of 5-HT. So it should not have any adverse interactions with escitalopram.

Also, it up-regulates SERT expression as well. This might actually protect the body from serotonin syndrome, as it makes more SERT binding sites available for re-uptake of 5-HT. What implications that has on the effectiveness of your escitalopram, I am not sure.

Side note, is the SSRI helping your depression at all? Having gone through depression myself, and experiencing how shitty SSRIs make you feel, I would think you would like to get off of it. It is effective for some people. However, I think there are much better ways to tackle the issue.

http://www.ncbi.nlm.nih.gov/pubmed/21129470

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