Comment · Sun, April 21, 2013

can we do a 6-APB AMA?

Original post in this thread

[deleted] · 48 points

Or any drug AMAs in geneal, there are alot of drugs that are not on the list. It's also fun to read them =)

What they were answering

ebolaRETURNS · 1 points

MDMA too is a potent 5ht2b agonist. In fact, some studies suggest that 5ht2b agonism partially mediates serotonergic release for entactogens.

u/MisterYouAreSoDumb

Yes, but the agonism from 6-APB is much greater. It actually has a higher affinity for 5-HT2B than drugs used to test that subreceptor. If you take 6-APB, you'll immediately realize how much more potent of a vasoconstrictor it is.

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