Comment · Sun, April 21, 2013
Original post in this thread
[deleted] · 48 points
Or any drug AMAs in geneal, there are alot of drugs that are not on the list. It's also fun to read them =)
What they were answering
metocin · 2 points
Good to know. I can handle stimulants just fine, but psychedelics always make my body uncomfortable.
u/MisterYouAreSoDumb
It's the 5-HT2B agonsim that is doing it with 6-APB. Other RC psyches can have some affinity for this sub-receptor too.
Comment · Sun, April 21, 2013 · 1 pts
Having now done both, pure MDMA is better. I liked aspects of the 6-APB, but the vasoconstriction was too much. I still have one capsule left. When I take that one, I will load up on taurine, L-glutamine, and kratom to c
Comment · Sun, April 21, 2013 · 2 pts
The soreness is a direct result of the vasoconstriction. It's very bad at times. If my plan to use taurine, L-glutamine, and kratom doesn't work, then I'm writing off 6-APB.
Comment · Sun, April 21, 2013 · 1 pts
Yep, it's not something to be taken lightly. I had hoped the affinities with 6-APB would be less, but it was significant.
Comment · Sun, April 21, 2013 · 1 pts
Really? That's the one thing I see in every anecdote. Some get it worse than others. I got it pretty bad.
Comment · Sun, April 21, 2013 · 1 pts
Yes, but the agonism from 6-APB is much greater. It actually has a higher affinity for 5-HT2B than drugs used to test that subreceptor. If you take 6-APB, you'll immediately realize how much more potent of a vasoconstric
Comment · Sun, April 21, 2013 · 1 pts
For me I got very tense in my shoulders, my feet fell asleep, and I was cold. I also had lasting muscle tension for a couple days.
Comment · Sun, April 21, 2013 · 1 pts
I have bad circulation normally, so I'm more susceptible to it. Some people might not notice it, but it's still there for sure.
**I'm going to copy what I wrote on another thread:** _____________________________________________________ YES! Keep your damn body temperatures down people! http://www.maps.org/publications/1998_malberg_1.pdf http:
Ativan (lorazepam) I was going to the Markus Schulz concert one night, here in Phoenix. At dinner, one of my friends rolls a pill across the table to me. He said it was an Ativan. I was like, ohh ok, thanks. I did not i
This is probably going to be the first in a series of discussions I start about MDMA. There's just too much information for one post. Therefore, I am going to start with one that is very interesting to me: MDMA's metabol
>Molly is like the 70s version of crack Wait, what? I think they got their equivocation backwards, and their demographics mixed up. >but because the drug is so highly addicting, he said, "They're buying a lot of it."
Don't ever admit anything to a police officer. EVER! The burden of proof is on them.
Replying to Mentran · Why no redosing?
The metabolism characteristics of the drug mean that the first dose inhibits the main metabolic pathway, CYP2D6. This means that any subsequent doses are more likely to use the secondary metabolic pathway, CYP3A4. The CY