Comment · Thu, March 21, 2013
Prozac after MDMA?
Original post in this thread
[deleted] · 7 points
After talking to a friend of mine, I'm interested in a combination of things going into a roll in the next few weeks. My friends says I should take 1200mg piracetam for 4 days before and the day of my roll, and for 4 days after.
He also says that I should pre/post load with 5htp, which I already do.
The only thing he says that scares me-he wants to give me a prozac to take 3-6 hours after I roll which he says will decrease the chance of neurotoxicity and prevents too much dopamine being released and reabsorbed. From everything I've read in this sub, SSRI's and MDMA do not combine. But would that actually make sense for after a roll?
Also, thoughts on the piracetam supplement? How much would it affect the roll? What would be a dose for a light/medium/heavy roll if I take piracetam beforehand since it potentiates MDMA?
What they were answering
Borax · 1 points
I never get a comedown, but then I do keep my doses conservative. All I really want is banishment of the blue in the following days - 5-HTP helps but I think the problem is that I wish I could be back there and not sitting at work with people who have no idea what it's like
u/MisterYouAreSoDumb
Well remember, tryptophan hydroxylase is lowered due to the ring-hydroxylated metabolites of MDMA and MDA. MDA's metabolite can lower it by 90%, where MDMA's metabolite lowers it by about 60%. That is a big advantage to using grapefruit juice and preventing MDA from being created in vivo. I never get the blues the following week, ever. I used to before I figured out my supplementation plan, but not anymore. I am actually happy and upbeat for about 2 weeks after the roll. Of course I supplement 5-HTP and EGCG for 3 days after, but that's it.