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Comment · Tue, March 19, 2013

MDMA-Assisted Therapy for Social Anxiety in Autistic Adults: Protocol Submitted to FDA

Original post in this thread

MAPSPsychedelic · 13 points

On February 28, 2013, the protocol ( full protocol ) | synopsis ) for our planned study of MDMA-assisted therapy for social anxiety in autistic adults was submitted to the U.S. Food and Drug Administration for review. This will be a MAPS-sponsored collaborative study between Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center and the Stanford University School of Medicine. Social anxiety is prevalent in autistic adults, and often compounds the considerable social challenges faced by autistic adults. The main objective of this study is to collect data on the safety of MDMA-assisted therapy in autistic adults, and to use standard clinical measures to estimate the extent to which MDMA-assisted therapy may reduce social anxiety symptoms in this group. Even though we did attempt to obtain external funding from a private foundation, our letter of intent was rejected. Please consider donating to help complete this study.

Alicia Danforth, Ph.D.(c), will present the results of her research on the [MD…

What they were answering

FuzzyBacon · 1 points

Yeah now that I've read it in full it seems like it's either a single high dose or a smaller one with a redose, which seems absurdly high. Anecdotally my baseline tolerance to drugs is much higher than most people (it takes 2x the standard dose of most psychedelics to get me anywhere fun, and my tolerance to mdma seems to be 1.5x most of my friends), but of course anecdotal evidence is anecdotal and even then I have no way of knowing if that's at all caused by the autism.

u/MisterYouAreSoDumb

Yeah, that would be interesting to know if the autism is affecting baseline tolerance. I wonder what data MAPS has on the matter.

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