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Comment · Sat, December 29, 2012

Neural and cardiac toxicities associated with MDMA: Reversal of MDMA-Induced 5-HT Depletion by l-5-Hydroxytryptophan

What they were answering

spinbox · 1 points

They dosed the rats at 7.5mg/kg three times spaced 2 hours apart. So thats like 140lb person taking 450mg doses 3 times in a night. Thats pretty crazy if you ask me and not accurate to what the average person takes.

u/MisterYouAreSoDumb

Rat dosages are not directly translated to human. For rats take (7.5*6)/37, which gives you 1.21mg/kg. That would be three 76mg doses for a person weighing 140lbs.

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