Comment · Wed, December 12, 2012
Which are the most unique RCs/legal drugs out there? As opposed to RCs which 'mimic' the effects of illegal drugs
Original post in this thread
ibogaine-ibeginagain · 42 points
Many people would argue that legal drugs, particularly the RC market, exist only as a substitute for illegal drugs - many drugs are seen as 'copycats' of popular illegal drugs such as MDMA, especially with the influx of RCs claiming to be 'the next mephedrone'.
While I agree that there is some truth to this, particularly with regards to cathinone-based stimulants, I believe that many legal (or recently legal) drugs are as unique from illegal drugs as illegal drugs are from each other.
Which RCs/other legal drugs do you feel are unique in their effects, and why?
My list would be:
* MXE - for me, the best dissociative I have ever tried. I feel it bridges the gap between psychedelics and dissociatives. Some similarities with K and DXM, but nowhere near enough to call it a 'Ketamine/DXM substitute'
* DPT - probably the most unique RC tryptamine, the only way I can think of describing it is if DMT/Ayahuasca were a dissociative.
* AMT - both a tryptamine psychedelic AND a stimulant/empathogen? If it weren't for the ridiculously long duration and nausea this would be almost too good to be true.
* 4-HO-DPT - not tried this one, but it seems to be unique in that the effects are describ…
What they were answering
Borax · 6 points
My mistake, you're quite right it's an SRI.
u/MisterYouAreSoDumb
DXM's main metabolite, dextrorphan, is an NMDA receptor antagonist. That's what gives it the dissociative properties. Also, DXM possesses affinity for the sigma-1 receptor, which modulates calcium and sodium channels as well. It's a fairly unique substance, actually.