Comment · Tue, November 13, 2012 · Ceretropic
Is it better to focus on NGF promoting nootropics rather than racetams? I would think growing nerves would be somewhat of a permanent result?
Original post in this thread
HiyaGeorgie · 7 points
Not to say you have to choose one nootropic over the other but Noopept and Lion's Mane for example promote NGF, obviously with some data conflicting this as with anything, but it's a start. Do I have the wrong idea of NGF in thinking that newly grown nerves would stick around after drug use is discontinued to a certain extent where as piracetam type gains would rely heavily on the drug actually being active in your system?
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · Ceretropic
NGF and BDNF receptors down-regulate in response to sustained increases, so cycling your supplements is necessary. There is no one place to focus, since we are still early in our understanding of the mechanisms. Also, NGF has been shown to improve memory in old rats, but not young healthy ones, and may have detrimental too.