Comment · Tue, September 25, 2012

TIL that magic mushrooms can make you permanently more creative, curious, and inquisitive

What they were answering

suRubix · 1 points

Just wondering is nicotine classified as a dopaminergic drug?

u/MisterYouAreSoDumb

To some degree, yes. Nicotine binds to nocotinic acetylcholine receptors in the central nervous system. Dopamine binding neurons are often located at these receptors sites. Therefore, binding of nicotine to these receptors does cause a cascading release of dopamine. Nicotine and cocaine both activate similar patterns of neurons in the brain. However, nicotine releases far less dopamine than other drugs which would be considered fully dopaminergic, like cocaine and amphetamine.

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