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Behind the Scenes at Nootropics Depot: Inside Our Pharmaceutical-Grade Testing Labs 🧪

Replying to AAAUUUUAUAUAUUAUA · Whoopsie. Yeah thats what i ment, your 1:1. Im very surprised that the Amyloban is that "one sided". It really does not look like it, no clue if i can blame the wobbly baseline or …

> Im very surprised that the Amyloban is that "one sided". It really does not look like it, no clue if i can blame the wobbly baseline or if i just have to bite the bullet and get glasses. You have to look at the actual peak areas numbers below the chromatogram, and then look at…

The story behind the FDA raid of Nootropics Depot

Replying to Megatron_McLargeHuge · I though it was about Tianeptine. Or was that a different case?

Tianeptine, adrafinil, piracetam, aniracetam, oxiracetam, phenylpiracetam, pramiracetam, etc. You can read my long comment on it above. We had stopped selling tianeptine years prior to the government coming into our facility, but we were selling racetams and adrafinil on the ND s…

Ordering emoxypine

Replying to MystikTrailblazer · Jfc, all those resources spent on stopping emoxypine? I wasn't even aware it's illegal in the US rather messaging has been different, which is moot here anyway. Aside. Thanks for …

Not just emoxypine, but piracetam and the other racetams, tianeptine, adrafinil, SARMs, peptides, etc.

A Potential New Nootropic (SYNTHESISED AND TRIED) results

Replying to cmnews08 · It does seem the effects of modafinil are not tied to or symptomatic of any traditional CNS stimulants or nootropics. Its exciting to think the positives of modafinil don't disappe…

I agree. There is a novel mechanism under the hood of the afinils that we don't yet fully understand. Years back when we were doing all our synthetic research, my theory was that it was mediated by one of the 5-HT sub-receptors. That's one thing that led me to 9-Fluorenol, which…

A Potential New Nootropic (SYNTHESISED AND TRIED) results

This looks very similar to a modafinil derivative that I found in an old Cephalon patent years ago, and had synthesized for us. It had much higher dopamine affinities than modafinil. I beta tested it out on myself, and it was crazy effective! It was somewhat like halfway between…

MYSAD's Stack June 2024

Replying to 12342ekd · Sounds more like you got lazy and went for the easy, money making route. Do you realize that there’s a higher risk taking herbal extracts than synthetically created isolated compou…

So the some people were in the room with us the whole time! Easy money making route?!? Do you know the margins on synthetics and peptides? Some of these vendors have 95% profit margins. I know the cost of what they are selling. It's much much easier to sell the synthetics for cra…

Please be cautious on orders from Botany.bio - mistakenly labeled (and therefore adulterated unknown substance) from product found in my last order.

Replying to MettaMind · Can you please tell us more about the DEA allowing you to test scheduled substances? What kind of substances are you testing, and might this lead to your company being involved in …

Well to start probably mostly cannabis products, but we want to be able to test all scheduled substances as a DEA licensed and ISO certified lab. There are not many DEA licensed and ISO certified labs in the US capable of doing proper testing of scheduled compounds. When I tried…

Not sure this is the best advertising idea...

Replying to handemande1 · > Most of the products are Literally available To be fair, most all fish oil (various kinds), berberine, EGCG + piperine capsules, Adrafinil, racetams, phenibut, etc have been out…

We have gotten totally fucked by our tablet partners the past year. Like seriously, the industry is pretty much in shambles right now. It's a fucking mess. The berberine tablets got done, and all the barrels were delivered to our facility. Then we got a frantic call from them to…

Do you plan on having Adrafinil back in stock?

Replying to signalme · I have some that is super iffy. Would you run that?

Sure, I will PM you the details.

Do you plan on having Adrafinil back in stock?

Replying to cristobaldelicia · The last time I purchased it, it seemed much less potent, less effective, and the natural odor was diminished. And not just from ND. I also previously got some from a competitor, a…

Our adrafinil has been made in the same lab using the same synthesis methods and precursors for years. Unless you are referring to adrafinil from many years ago, it's been the same for a while. The color and smell is not associated with purity. Generally, the specific synthesis m…

Reddit AMA | In-House Lab Edition

Replying to ShouldReallyGetWorkn · I know one thing you need to get useful results from your equipment is reference standards. When you are coming out with a new product for which there are no reference standard…

> 2nd question if you have time: With all the recent supply chain woes and just general need for high QX, will it ever be possible for ND to do it's own in house synthesis for some products? We actually already are. It's taking longer than I wanted to scale up to larger productio…

Reddit AMA | In-House Lab Edition

Replying to JohnTorque · What is the product that took the most effort from your team to develop? Why?

The second one I would say has been difficult is adrafinil. This is one we have been selling since 2013. However, it's a very complex one for a number of reasons. Going all the way back to the Ceretropic days, some batches we would get in would be dark pink/orange. Other batches…

another Adrafinil shortage?

Replying to FalseJenga · Really appreciate all you're doing. Been using ND for a year and couldn't be happier with the product and customer service

Glad to hear that! Thanks for the continued support!

Why is EVERY lions mane brand Chinese

Replying to odder_sea · I'm really tired of the "American rule" that allows big corps to bully smaller companies into submission with frivolous lawsuits and forces the little guy to concede or pursue a py…

It really depends on the product. To do the full panel we do on synthetics at a 3rd party ISO certified lab would likely cost about $800-$1,500 per batch. Some things need specialized methods like 2D NMR, where other ones can use FTIR for ID, so it depends on the product. For exa…

another Adrafinil shortage?

Hopefully not 8-9 months, but at least 1-2 months most likely. Sorry! We are working as hard as we can, but things are just not going our way this year.

Adrafinil coming back in stock ever? If not, recommended alternative? Thank you!

Replying to Spikel14 · Hey are they coming back again? I must just be missing the windows where it's in stock :(

Yeah, my team says they should be getting some up today.

NMN is back in stock!

Replying to Aldarund · why limited? if its in stock it shouldnt be limited as problem was with coating, not with shortage of materials

Sales are not limited for NMN. You can buy however many you want. I believe that is just a default statement in the in stock notify email. That's good to have for things like adrafinil and piracetam, who's supply are still a bit strained. However, it's not pertinent to NMN at the…

Phenylpiracetam outage

Replying to jmking555 · I understand! Thank you for replying 😁 mostly, it’s just strange because I’ve used ND 98% of the time for any nootropic I’ve purchased. I’ve never purchased phenylpiracetam anywhe…

There is no real place to get it made anymore. We have been building our own synthesis lab in the EU for the past year to take over production on it. However, that has just taken a lot more time (and cost a lot more money) than expected. It's the same thing with adrafinil. We jus…

Adrafinil coming back in stock ever? If not, recommended alternative? Thank you!

Replying to Kurbs3539 · u/MisterYouAreSoDumb, any update? :(

In case you didn't already see, they are back up on the site now.

Is there any problems with phenylpiracetam?

Replying to 3ric843 · Really? \* makes a bit of research \* [Yeah... :(](https://www.reddit.com/r/NootropicsDepot/comments/e2qflu/regulatory_changes_in_china/) So it's the end of buying phenylpiracet…

Yeah, we finally ran out. However, we have been building our own synthesis facility for the past year. It's just taking longer than expected. Adrafinil was first. We just restocked that. Phenyl is next. It's not permanently gone. It will be back as quickly as we can.

Adrafinil coming back in stock ever? If not, recommended alternative? Thank you!

Replying to Beenks · We’re still waiting on that update, ND Curious if there is an ETA. Has anyone found a trustworthy source that has it in stock right now? Please PM If so!

Adrafinil capsules will be back on the site this week!

Adrafinil coming back in stock ever? If not, recommended alternative? Thank you!

Replying to HistoricalAd9671 · Any updates on what the expected time for the resupply could be?

Do you mean for this time, or for a resupply after this batch is done?

Phenylpiracetam Capsules Out of Stock

Yep, it is a similar supply chain issue to adrafinil. Luckily this one should be resolved a lot quicker. We should have more phenylpiracetam raw material arriving this week. We will get it into the lab and through production ASAP.

Adrafinil

Replying to ThinkingSalmon · More like six months

Adrafinil went out of stock on 04/12/21. That was 2 months and 8 days ago.

A D R A F I N I L update please????

Replying to Kurbs3539 · Don’t mean to prod but an update would be appreciated so I can plan my orders. u/MisterYouAreSoDumb

I am hoping to have adrafinil capsules back in stock in 2-3 weeks or so. Powder might be slightly longer. We will work to get them up as fast as we possibly can.