Comment · Wed, February 11, 2026 · Nootropics Depot & Natrium Health
Ashwagandha almost killed my liver – bilirubin hit 50 mg/dL, severe jaundice & itching for months. My warning story (21M)
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FitComplex2444 · 629 points
21M here. Had bad social anxiety, shyness, low self-esteem. Someone said Ashwagandha (Carbamide Forte 500 mg) would help with stress & confidence.
Started 500 mg daily, sometimes 1000 mg. Took it straight for ~4 months.
Then disaster.
Severe fatigue → constant heartburn → whole-body itching so bad I scratched feet, scalp, hands until I had open wounds & scars. Skin underneath was yellow.
Jaundice hit hard. Bilirubin went to ~50 mg/dL (normal <1.2). SGOT/SGPT 400–600+. Liver basically stopped working.
Hospitalized, IV fluids, strict diet, 4+ months of hell. Couldn’t sleep, felt disgusting about myself, thought I was dying.
Everyone blamed “hot food” or “contaminated stuff”. I believed it too. Stopped Ashwagandha, got partial recovery (enzymes dropped, liver size came down from 17.7 cm → ~14 cm).
Then I stupidly started again thinking “maybe it was something else”. Symptoms came back worse.
Finally searched Reddit and saw dozens of similar stories — liver injury, high bilirubin (10–50+), itching scars, same brands.
I hate myself for not searching earlier.
Questions for anyone who’s been through this:
Did high-dose Ashwagandha (500 mg+) cause liver damage/jaundice for you too?
How lo…
What they were answering
Original_Pride_5451 · 67 points
Carbamide Forte is not a good brand. It could be a brand issue.
u/MisterYouAreSoDumb · Nootropics Depot & Natrium Health
I would bet money they have withanone in there, which is known to be hepatotoxic.
I'll buy some to run through the lab. Withanone comes out around 13.2 minutes in our UPLC method. If it is in there, we will see it.