Comment · Mon, December 1, 2025 · ND Owner
Perika discontinued - any plans to take over the SJW extract?
Original post in this thread
random-username-666 · 11 points
Hi ND Team! I've learned recently that the only hyperforin-standardized St. John's Wort extract out there, WS5570, sold under the brand Perika by Nature's Way, has been discontinued.
I know ND has been looking to do an SJW extract like WS5570 for a while, but has always run into a brick wall with Nature's Way owning the patent/rights/whatever, but perhaps now that they've abandoned their WS5570 product, ND could pick it up and offer a WS5570 product of their own? It's truly been one of the few things that has worked for my mom to help with depression and effectively get off SSRIs. Would be a shame to lose this helpful tool!
What they were answering
MrRADicalKMS · 2 points
Woah, super exciting! I haven't tried Isoliquiritigenen just yet, but that sounds almost too good to be true! Lmao. I knew Isoliquiritigenen was a great supplement, but the main commenters post made it sound even better than I thought it was. It's one I've read about here and there, and the product page (awhile ago), but haven't REALLY looked into it. It seems to be more potent than I initially thought!
Additionally, I thought Saffron was better than it for depression, but are they actually about equal? Crazy stuff, and now I have to try it sooner than I was originally going to! Has anybody on your team combined them together? How would that fair?
u/MisterYouAreSoDumb · ND Owner
Isoliquiritigenin is a super cool compound limited by bioavailability. I think most people that don't notice anything from it are just not getting it into the body. The new delivery system should allow those people to actually feel its effects.
What's better for depression is going to depend on the person, as everyone's depression is different. We often talk about it like it is a singular thing, but depression manifests itself very differently for different people. I have combined saffron with isoliquiritigenin and kanna. I really love the effects of them all combined. I can't really get too much serotonin, as I am naturally low in it, so it works for me. It might not work the same for everyone, though.