Comment · Wed, October 15, 2025 · ND Owner
Myostatin Mushroom
Original post in this thread
runnerglenn · 30 points
Any update or estimated timeline on this. Was reading old threads and looks pretty exciting and novel.
What they were answering
Warren_sl · 3 points
That is incredibly exciting stuff
u/MisterYouAreSoDumb · ND Owner
Just for reference, Pendulum's Akkermansia is 100 million AFU, and it is just normal unprotected powder in a normal capsule. Ours is going to be 20 BILLION cells in the 3 stage microencapsulation delivery system. It's going to be 10B CFU of live and 10B TFU heat-killed. AFU and CFU are different measures, too. AFU (Active Fluorescent Units) measures all metabolically active cells using flow cytometry, while CFU (Colony Forming Units) measures only those cells capable of reproducing on a culture plate. AFU is always shows higher, as it includes non-culturable but active cells, whereas CFU excludes them. CFU only measures cells that are culturable and replicable, which is what you want in a probiotic. So ours will have at least 100X more live Akkermansia cells than Pendulum, in a delivery system that protects them and helps them actually culture in your GI tract. Then it will have an additional 10B heat-killed that can go directly to work as a paraprobiotic.