Comment · Fri, September 12, 2025 · ND Owner
What’s new with NMN?
Original post in this thread
inamsterdamforaweek · 5 points
Hey all,
It’s been two years since i tried NMN and for the month i was on it ( 125mg from ND) it was amazing, felt invincible, full of energy etc. i stopped because my Homocysteine was elevated and I heard that NMN mjghr have been the culprit.
Since then I took folates, aspirin daily and tbh my homocysteine is stil elevated…i am unsurw at this point if this is just my genetics, or if NMN forever changed this.
But I want to get on NMN again, cause I miss that feeling and maybe it voukd be safe at half dose…i am unsure :)
So any advice is appreciated but also curiius if rhere is bee consensus with it as I remember reading that it fell out of grace toferher with Sinclaire.
Thanks!
What they were answering
inamsterdamforaweek · 3 points
So just to be clear: OptiNAD+ contains tmg so it shoild prevent homocysteine issue? That is cool. And the effect is similar?
I an tempted to try glutathione never did and heard good things about it.
My homocisteyne is still elevated even after taking a lot of tmg etc…which is why i am hesitant to jump on this again.
u/MisterYouAreSoDumb · ND Owner
Yes, we added TMG to account for that effect that NMN can cause. If your homocysteine is still high without NMN, then you are likely an undermethylator, and would benefit from some supplements to address it. Methylcobalamin is a good idea. We have Super B12, or you can take Infini-B, which has methylcobalamin and the rest of the Bs. Then I would say probably reduced glutathione daily would be a good idea as well. You can of course take TMG by itself without NMN to start, if you want to do that before starting NMN again.