Comment · Sat, December 3, 2022 · ND Owner
Can someone explain this please?...
What they were answering
GradualDIME · 11 points
The two ketones in most racetams participate in hydrogen bonding with water — a similar effect is noted with piracetam, although to a greater extent since piracetam lacks the fatty dimethyl groups that are attached to pramiracetam.
The gel like appearance is due to its density, and the “strings” are just dissolved pramiracetam that has yet to be homogenized in solution, but with stirring you should find that it homogenizes well. The effect is rather hypnotizing, isn’t it? I had fun watching the same thing when recrystallizing piracetam recently. The thought is, that they are participating with hydrogen binding between other pramiracetam molecules, and that they are attracted to themselves post-dissolution, especially since you are allowing them to dissolve without manual agitation.
Speaking of which — the hygroscopic nature of the racetams also makes it difficult to recrystallize.
u/MisterYouAreSoDumb · ND Owner
You are correct! I think many people are confused, as everyone online parrots around the "pramiracetam is fat soluble" statement, and most people don't understand the chemistry of solubility. This means they get confused when pram dissolves in water. "I thought it was fat soluble?!?" Well, it is. It's also water soluble.