Comment · Thu, August 25, 2022 · ND Owner
why isn't ecdysterone complexed with cyclodextrin?
Original post in this thread
samuelx23 · 10 points
So the literature seems to indicate that ecdysterone has low water solubility and thus low abortion orally. When conplexed with beta cyclodextrin it seems to have much high solubility and theoretically higher bioavailability. Because of this I wonder why ND doesn't sell a complexed version? Although I know guerilla minds turkesterone is controversial there product is supposedly complexed this way. Anecdotally I found this to give massive benefit. Are you guys taking higher doses of 20E to account for this? Am I missing something?
Poor bioavailability
https://www.google.com/url?sa=t&source=web&rct=j&url=https://www.mdpi.com/2227-9059/9/5/492/pdf&ved=2ahUKEwjlusOj2tr5AhXrk4kEHcn6BFMQFnoECAcQAQ&usg=AOvVaw1UaFF8k25MHizLT2OvG1yA
Compmexex cyclodextrin and 20E has better water solubility
https://pubmed.ncbi.nlm.nih.gov/30458190/
In vitro simulation of stomach environment increased absorption
https://pubmed.ncbi.nlm.nih.gov/35311602/
What they were answering
just702vibin · 2 points
Love the jay z quote! 🤣
u/MisterYouAreSoDumb · ND Owner