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Comment · Wed, June 8, 2022 · ND Owner

Interactions checker would be extremely helpful for a lot of us

Original post in this thread

AvgAIbot · 33 points

An interactions checker for ND products would be awesome.

Many of us end up having big stacks; it’d be nice to know if any products didn’t play well with each other.

I know it’s a huge project. An easier step would be to maybe put a warning on the product page for products that have specific bad interactions.

Or am I just misinformed and pretty much any ND products can be taken together without serious issues?

What they were answering

[deleted] · 1 points

[deleted]

u/MisterYouAreSoDumb · ND Owner

Yep, you can take reduced glutathione any time, because it just goes right to work as glutathione. It doesn't have to go through a redox step to get there.

Wine is very complex, and the hangovers you can get from wine are different than other alcohol products. The tannins are part of that, as are the sulfites and natural histamines found in certain wines. With wine specifically, it's less about the ethanol and more about the thousands of other compounds in it. Some wines give me mild allergic reactions, which increases TNF-α, which exacerbates ethanol-induced toxicity. This is why I have been using Immune Defense after drinking more and more. A customer of ours turned me onto it. He said that if he took Immune Defense after drinking that he never got hungover. He was not expecting it, but it works. So I started trying it, and sure enough it did! I think that is due to its ability to lower TNF-α like NAC can. TNF-α is a potent mediator of inflammatory responses. A lot of those things in wine are likely causing inflammation through TNF-α, which then makes the ethanol damage worse. Blocking that can help both.

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