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Comment · Thu, April 21, 2022 · ND Owner

liposomal l-carnitine

Original post in this thread

Goh77 · 2 points

Why it doesn't exisit yet?

What they were answering

bellerotoo · 6 points

Minor point, but the vaccines are lipid nanoparticles, not liposomes. Liposomes are vesicles with hollow/water-filled (unless multilamellar) cores while the vaccine LNPs have electron dense innards with a substantial lipid component which does not display obvious lamellae. LNPs are generally easier to make than liposomes since their formation is assisted by ionic complexation between mRNA and ionizable lipid.

u/MisterYouAreSoDumb · ND Owner

Lipid nanoparticles are liposome-like structures, but you are right. They are slightly different. I guess it is similar to how all cubes are rectangles, but not all rectangles are cubes. My main point is that both liposomes and LNPs are completely different than emulsions, where you just mix things with lecithin. You can't just mix shit with sunflower lecithin and call it a liposome, which is what everyone is doing in supplements right now.

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