Comment · Wed, March 2, 2022 · ND Owner
MYASD is great
Original post in this thread
yourgymbro01 · 79 points
Honestly replying to me in just a few hours when you're the owner of a company that sells all over the world, it's a great thing. I'm actually amazed.
What they were answering
TurquoiseGroundhog · 2 points
How did you verify safety of the novel compounds? Where they just modifications of existing compounds or from scratch? Could you give any insight on the process of how you went about designing them? Any computer tools? Animal testing? In vitro testing? Any receptor affinity tests? Did you conduct any blinded trials (even if only on yourself) - how significant were results? What percentage of test compounds are effective?
Sorry for all the questions - sounds like you're working on pretty interesting stuff so hopefully you can elaborate in a way that wouldn't reveal anything too proprietary...
u/MisterYouAreSoDumb · ND Owner
Basically some educated guessing based off affinities of other compounds, AI binding/target prediction using some modern tools, and the Shulgin method of starting very low in dose to see how you react, then moving up from there. Some of them were modifications to existing compounds. Others were from scratch. No animal or blinded studies yet. Much too early in the process to dump that kind of money on things. It has been more like applying Alexander Shulgin's process to nootropics/biohacking with access to a lot more information and modern tools. Every compound we have developed so far has had effects. Whether they are effective for specific things in double blinded trials has not been established. We also stay away from things that we know have risky binding affinities. Opioid and other receptors that have the risk of serious acute side effects we avoid. We are not making recreational things. They are more for cognitive enhancement than anything.