Comment · Wed, December 16, 2020 · ND Owner
Original post in this thread
Translation333 · 5 points
What are the best nootropics taken before drinking to reduce alcohol damage?
What they were answering
Parent comment was not in the public dump (deleted, or never archived).
u/MisterYouAreSoDumb · ND Owner
My pleasure!
Comment · Tue, December 15, 2020 · 9 pts
That's only if you did not take it before starting drinking. As long as you took the NAC before starting drinking, you can take it during as well.
Comment · Tue, December 15, 2020 · 5 pts
N-acetylcysteine and emoxypine are the two main ones for pre-drinking. I also add in tart cherry now for the uric acid effects. A good B complex and some electrolytes would not hurt, either.
Comment · Sat, December 19, 2020 · 2 pts
Kind of. NAC increases glutathione, so you get similar effects to taking it as an exogenous source.
Comment · Tue, December 22, 2020 · 3 pts
[A dual effect of N-acetylcysteine on acute ethanol-induced liver damage in mice](https://sci-hub.do/10.1016/j.hepres.2005.12.005) >We hypothesize that local redox environment might influence the effect of NAC.Before
Comment · Wed, December 23, 2020 · 2 pts
Cannabis can be useful for many people at the appropriate dosage. It's just many people go way over that. What specific side effects would you like to see addressed in a product like Canna Defense?
Comment · Tue, December 29, 2020 · 1 pts
My pleasure!
Comment · Tue, December 29, 2020 · 1 pts
Interesting! This is the first time I am hearing about some of these side effects from cannabis. I will have to research a bit on them. >Excessive cannabis use can also lead to the desensitization of dopamine receptors
Comment · Fri, January 1, 2021 · 1 pts
I have considered hydroxytyrosol before. It would be a good addition.
Comment · Wed, April 7, 2021 · 7 pts
Then please explain the mechanism behind NAC-exacerbated liver toxicity to me.
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