Comment · Mon, November 2, 2020 · ND Owner
Will quercetin mess with my testosterone?
Original post in this thread
ArtificialBrain808 · 4 points
Confused about the relationship between this stuff and estrogen. Bought it to add to my recovery stack but saw someone on here mention it it may affect estrogen. I was also wondering if it is safe for my wife to take? I did find this paper that seems a bit alarming:
Dietary Quercetin Exacerbates the Development of Estrogen-Induced Breast Tumors in Female ACI Rats
On an unrelated note the new tart cherry extract seems extremely effective so far. Only tried it for two days but do see a noticeable decrease in my usual back pain after working out.
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · ND Owner
Stimulating effects of quercetin on sperm quality and reproductive organs in adult male rats
Quercetin prevents 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin‐induced testicular damage in rats
Alleviative effect of quercetin on rat testis against arsenic: a histological and biochemical study
Beneficial effects of quercetin on sperm parameters in streptozotocin‐induced diabetic male rats
It seems to have a positive modulating function on testosterone. The study you linked is more to do with inhibiting COMT, which exacerbated breast cancer in genetically modified rats prone to a fuckload of genetic issues. ACI rats are an inbred type of rat used because they are bred to get sick and die. It's not an indication of how something will act in a healthy human.
Glad to hear it on the tart cherry! It's one of my favorites now as well.