Comment · Fri, October 9, 2020 · ND Owner

I don’t think I have enough. What do you guys think I’m missing?

What they were answering

iwantmyownname · 2 points

Might have been this study

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082882/

The results state if I'm reading it correctly, mentions nearly 20% also mentions variants of cyp1a2

The title states a significant effect so I'm not sure if the two studies are the same with the ones you linked and this one

u/MisterYouAreSoDumb · ND Owner

Ohh wow, that one is interesting! So it does significantly inhibit caffeine metabolism, but it is not related to CYP1A2. The study I posted was specifically looking at CYP1A2. So if it is not affecting that pathway, but modulating caffeine metabolism through another, it would not have seen that.

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