Comment · Thu, July 23, 2020 · ND Owner
Polygala Tenuifolia side effects: paraesthesia, tingling and foot pain
Original post in this thread
_vasilescu · 7 points
There's been a lot of talk about Polygala lately, happy to see people find it useful, but I thought it would be worthwhile to report these side effects as I haven't read about anyone experiencing them before with this nootropic.
To get to the point, I began taking 3 x 100 mg of ND's 20:1 Polygala per day and by the 3rd day, I started getting paraesthesia and a tingling sensation all throughout my legs. The following day, I experienced mild foot pain - the soles of my feet literally hurt while walking.
Furthermore (and this might have been just my mind playing tricks on me) I felt scratchy everywhere all day.
Increasing NGF is probably the culprit here, though I haven't been able to find out or understand why some people experience paraesthesia while the majority don't, or if it's even possible to combat this side effect.
I had a similar experience with NSI-189 (as did others), but back then I stupidly tried to push through it and woke up one morning with the soles of my feet hurting so badly that I literally limped in my house for 3-4 days and was unable to go out.
Similar (but much less intense) experience with NAC, and I imagine I'd probably get the same thing if I tried…
What they were answering
_vasilescu · 1 points
Thanks a lot for your help, appreciate it! Good to know there's nothing concerning going on.
Will drop to 100 mg and see how I get on in a few days. In the meantime I'm trying the NMN!
u/MisterYouAreSoDumb · ND Owner
My pleasure! Let me know how you like the NMN.