Comment · Fri, May 22, 2020
Magtein Withdrawal
Original post in this thread
eamonn123 · 4 points
I just bought some magtein from ND. I just say that there seems to be a significant withdrawal affect when you stop taking it. Is that true and something I should be worried about? Thanks
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb
It's not something you should be worried about. However, you are not crazy. I get it, too. I am still trying to figure out the mechanism behind it. It might just be getting magnesium to the brain really well, and the drop in magnesium is leading to the effects. It could also be something to do with DKK1 (Dickkopf-related protein 1) expression by the threonic acid. Increased DKK1 is implicated in both Alzheimer's and hair loss. Because magnesium L-threonate is a magnesium ion chelated to threonic acid, it could be resulting in increases of threonic acid in the brain as well. Threonic acid results in attenuation of DKK1 expression. Perhaps the rebound effects of that are what we are feeling.