What's the deal with sarcosine? Is it coming back any time soon?

Comment · Mon, February 3, 2020 · 3 pts

Yes, it is in production now. We had an issue with the particle size of the powder not behaving with the tabletting process. So we had to make slugs of the powder, then re-mill it before it would successfully stay in tab

Comment · Mon, February 3, 2020 · 2 pts

We are reforumlating berberine into a much cooler tablet formulation. That's one powder that just does NOT play well on encapsulation machines. It forms a clay-like consistency, and makes consistent fills very hard. So w

Comment · Tue, February 4, 2020 · 3 pts

You are certainly on the right track! ;-)

Comment · Sat, February 15, 2020 · 2 pts

A pharmacokinetic study? Those are expensive. We don't sell nearly enough berberine to justify it. Perhaps if interest picks up on it, but we are not patenting this one. So it will be hard to justify spending money on a

Comment · Tue, February 18, 2020 · 2 pts

Our formulation will have studies behind it. It's just that those studies have already been run by other people ahead of time. We won't be running our own, but that does not mean there is not research on it.

Comment · Thu, February 20, 2020 · 1 pts

Berberine passed the BBB easily. So as long as you can get plasma levels high, you are going to get it into the brain.

Comment · Sat, February 22, 2020 · 1 pts

I'll have to brainstorm a bit on how one might down-regulate P-glycoprotein, or at least prevent the up-regulation.