Bacillus coagulans GBI-30 6086 and its tyndallized sister product "Staimmune". Extremely resilient and thermostable probiotic with potentially body-wide regenerative properties.

GanedanBC30's heat-inactivated version of their probiotic, trademarked as staimune, may mobilize endogenous bone marrow-derived mesenchymal stem cells indirectly by significantly upregulating granulocyte colony stimulating factor. Staimune also decreases the levels of Granulocyte-macrophage colony-stimulating factor which has a role in increasing inflammation in response to food allergies and asthma. (in-vitro findings)

> Inactivated B. coagulans GBI-30-treated PBMC cultures showed a robust increase in G-CSF levels, reaching over 7,000-fold above untreated cultures at the highest dose, in contrast to mildly reduced GM-CSF levels. This is an important differentiation, since G-CSF supports stem cells to produce neutrophils, whereas GM-CSF promotes the production of multiple cell types, including eosinophils, involved in immune defense against multicellular parasites and also in inflammation in allergies and asthma. In addition, G-CSF is used therapeutically to support stem cell mobilization, migration, and tissue repair.40 Therefore, the selective effect of inactivated B. coagulans GBI-30 cells on growth factor production may be directly beneficial in repair and regeneration of th…