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Comment · Wed, October 31, 2018

Question about Terpene/Polyphenols testing

Original post in this thread

obliviron · 3 points

Hi, I have bought Lion's Mane in the past and I was wondering why the Terpene content isn't tested. Beta-Glucans are important, but they are likely secondary to the alkaloids in terms of importance for the effect profile of Lion's Mane. Can this be tested for? I understand other companies wanting to sell a lesser or shady product and not even test for B-Glucans, but now that Nammex is providing standardized B-Glucans every vendor that sources from Nammex is advertising B-Glucan content. Knowing the Terpene and the content of alkaloids unique to Lion's Mane would be more indicative of the quality of the extract.

What they were answering

Kostya93 · 1 points

The core of the 'problem' with supplements is and always will be:

do you trust:

- the vendor and his in-house lab (sorry, but I do not trust in-house testing and proprietary analytical methods. It is in essence subjective and therefore unreliable. Or is it just me being paranoid? BTW, who still trusts Paul Stamets' products and claims ? An in-house tester, obsessed with control and his mission)
- the third party lab (some labs do not actually test but simply confirm the vendors technical data sheet: "dry labbing". Some labs make mistakes. Where there are people there are mistakes. Using several labs is an option to minimise errors.)
- the vendor is testing the actual product he's selling to the consumer (there's Aloha Medicinals, who has extracted versions of their products tested and then used those test reports to market their ground biomass powders online)
- reviews / testimonials (all of which are for sale and in the core mean nothing)

There is no easy solution I guess.

Personally I trust third party labs and their test results. But only if those test results are repeated on the supplement facts panel of the product.
Lying about your specs on the official supplement facts panel can have you prosecuted and fined and you will be crucified in social media and on the internet. You can kiss your company and reputation goodbye then.

Which is probably the main reason most…

u/MisterYouAreSoDumb

sorry, but I do not trust in-house testing and proprietary analytical methods. It is in essence subjective and therefore unreliable.

But you trust results from a lab that you have not verified the results of? How does that make any sense? Do you not trust in-house lab results because you don't have an in-house lab, and don't understand that analytical chemistry enough to know how to verify the validity of the methods? How do you think these "industry standard" methods come into existence? They are created in a lab and then verified. There are actual people creating these methods and verifying them. This is why I hired one of those people. Now I can sit and talk with him about the chemistry of why we can be sure something is valid or not, and actually see the analyses being run with my own eyes. Trying to pass that off as LESS RELIABLE than a PDF from a lab that you just have to trust is just disingenuous.

the third party lab (some labs do not actually test but simply confirm the vendors technical data sheet: "dry labbing". Some labs make mistakes. Where there are people there are mistakes. Using several labs is an option to minimise errors.)

Yes, fake labs are a big problem. Also, most labs use their own in-house analytical methods that they developed and tweaked for their machinery. They also won't show you those methods. They keep them proprietary. So how can you know they are not tweaking them to mask an impurity peak, or something like that? You have no idea, because all you are doing is getting a PDF of a result, and have no way of verifying the testing was done correctly, or with valid methods. I do, because I can rerun the methods in my lab, and verify if we get the same results.

We also still use many 3rd party labs. You keep talking about this as if it is one or the other. We do BOTH! We can have a lab like Alkemist, or Mérieux, or Eurofins run a test, then we can also run the test on our equipment and compare the results. That's how you validate things. This is also how we catch mistakes by other labs. To play off the lack of an in-house lab as anything but is disadvantage is seriously misguided. Having an in-house lab can only help you ensure quality standards. The 3rd party labs are still there if you need them, and they are still there to validate your own results if needed.

Personally I trust third party labs and their test results. But only if those test results are repeated on the supplement facts panel of the product. Lying about your specs on the official supplement facts panel can have you prosecuted and fined and you will be crucified in social media and on the internet. You can kiss your company and reputation goodbye then.

I am not sure where you are getting this idea from. You have said it before, but there is nothing in CFR Title 21 that says you can lie on the other parts of the label, but have to be honest in the supplement facts panel. That's just silly. The label claims needs to be accurate on any part of the label. Furthermore, the FDA is only one thing you have to worry about. It's the FTC that goes after companies for making false claims on their products, and they are even more ruthless than the FDA. They don't give a shit where you make the statement; be it on the label, on your site, on the COA, or in an email. They will bring the hammer down on you no matter where the false claims are. So I have no idea where you are getting the idea that things need to be in the supplement facts panel for them to hold weight or be treated seriously. All statements a company makes need to be true and verifiable. To top it all off, then you have to also consider civil suits. That just goes based on common law. So you can be sued for statements without the FDA or FTC even being involved.

(there's Aloha Medicinals, who has extracted versions of their products tested and then used those test reports to market their ground biomass powders online)

Not that I am surprised, but do you have evidence they are doing that? Again, I would not doubt it, but you seem very confident in that claim.

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