Comment · Fri, February 9, 2018

Comprehensive Guide to the Best Anti-Aging Supplements

What they were answering

Hormesis · 3 points

We had a conversation about this years ago, where I messaged you shortly after trying some Niagen. I was pretty excited because I felt super energized, like I could do anything.

The trouble is that this lasted maybe a week. I've never felt it since, despite trying various brands off and on over the years.

I've experimented with hundreds of nootropics and supplements over the years, and like to think that I'm not especially prone to the placebo effect, but it's certainly possible.

u/MisterYouAreSoDumb

I remember that. It certainly could have been a response your body had to increased NAD+ levels in your liver causing some sort of signal cascade. Then perhaps your body got used to it, and you never felt it again. I would be interested in seeing if you respond well to nicotinamide mononucleotide.

Other MYASD lines in this thread

Comment · Fri, February 9, 2018 · 5 pts
The research behind NAD+ is interesting. However, I am not yet convinced that supplementation of nicotinamide riboside increases plasma levels enough to justify the cost. It seems to elevate it in the liver, but that doe

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