Comment · Thu, February 8, 2018 · Ceretropic & Nootropics Depot
Cordyceps and Caffeine
Original post in this thread
NippleSauce · 8 points
Hello all,
I’ve been looking into cordyceps for quite a while now as I figured it might be worth a shot as a libido booster. Unfortunately, I am an avid coffee drinker and I’ve seen many people mention that you should not be consuming caffeine while taking cordyceps.
From the looks of it, the primary argument is that cordyceps binds to the adenosine receptors which causes an upregulation of the StAR enzyme (which transports cholesterol into the mitochondria where it is cleaved and thus can eventually lead to steroid/testosterone synthesis). Caffeine, however, is an adenosine inhibitor and thusly would obstruct the cordyceps from binding to the adenosine receptors, thereby rendering the supplementation useless.
While this makes sense, the confusion starts to come into play when we look at caffeine’s affect on testosterone. I’ve stumbled across numerous studies that mention caffeine increasing testosterone levels in males when taken before exercise. In some cases, this caffeine supplementation lead to a testosterone increase of around 14%!
This is intriguing because of caffeine’s adenosine inhibiting ability. Shouldn’t cortisol levels spike and cause testosterone to d…
What they were answering
NippleSauce · 1 points
I can't believe I missed your reply yesterday! Do you happen to have the source for the study that found cordyceps to have a cAMP-independent and StAR-independent pathway for steroidgenesis regulation?
That sounds like a very interesting read!
Would you also happen to know what is considered a "normal" dose of cordyceps. I have been taking 1g of militaris from RealMushrooms daily in the morning on an empty stomach.
Oh, and thanks for the reply! Sorry for poor formatting, I'm currently on mobile
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
Do you happen to have the source for the study that found cordyceps to have a cAMP-independent and StAR-independent pathway for steroidgenesis regulation?
Sorry, this was not in relation to cordyceps specifically. This was just a study showing there was a mechanism for cAMP-independent signaling regulating steroidogenesis. I just postulated it might pertain to cordyceps.
Would you also happen to know what is considered a "normal" dose of cordyceps.
1 gram is pretty normal.