Comment · Thu, June 29, 2017

Will a tolerance build to NAC's glutamate reducing effect?

Original post in this thread

NoveltyAccountsSuck1 · 3 points

I read that it induces the release of glutamate into the extracellular space where Group II mGluRs are located via the cystine-glutamate antiporter. And that these receptors are negative regulators of glutamate release.

Source from where I read this: https://en.wikipedia.org/wiki/Cystine#Biological_transport

So would there be tolerance to this effect?

What they were answering

NoveltyAccountsSuck1 · 1 points

/u/misteryouaresodumb

u/MisterYouAreSoDumb

It's hard to say for sure. I would imagine there is some tolerance. However, it might allosterically modulate and maintain balance.

Other MYASD lines in this thread

Comment · Mon, July 17, 2017 · 3 pts
Are you referring to the below article for Scientific American? https://www.scientificamerican.com/article/antioxidants-may-make-cancer-worse/ I'd say the mechanisms seem to make sense, and it should be considered if o

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