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Comment · Tue, December 13, 2016 · Ceretropic & Nootropics Depot

There is no actual difference between Synapsa's and Bacognize's Bacopa extract. Or is it?

Original post in this thread

AdAstraPer5-HT2Ar · 13 points

I'm posting the answer to a comment saying that Synapsa was different from regular bacopa extracts and that it has 30 years of research backing its effects. Here is what I answered:

But read this:

https://www.researchgate.net/publication/260646738_Standardised_Extract_of_Bacopa_monniera_CDRI-08_Improves_Contextual_Fear_Memory_by_Differentially_Regulating_the_Activity_of_Histone_Acetylation_and_Protein_Phosphatases_PP1a_PP2A_in_Hippocampus

Contextual fear conditioning is a paradigm for investigating cellular mechanisms involved in hippocampus-dependent memory. Earlier, we showed that standardised extract of Bacopa monniera (CDRI-08) improves hippocampus-dependent learning in postnatal rats by elevating the level of serotonin (5-hydroxytryptamine, 5-HT), activate 5-HT3A receptors, and cyclic adenosine monophosphate (cAMP) response element binding (CREB) protein. In this study, we have further examined the molecular mechanism of CDRI-08 in hippocampus-dependent memory and compared to the histone deacetylase (HDACs) inhibitor sodium butyrate (NaB). To assess the hippocampus-dependent memory, wistar rat pups were subjected to contextual fear conditioning (CFC) following daily (post…

What they were answering

Eledex · 2 points

When might this better cheaper version be available to the interested public?

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

It depends on how our development goes. If everything goes right, then it should not take too long. If we run into issues, then it can drag on for a while. We are about to make some changes at ND that are going to give us more bandwidth to bring out all the new compounds we have been waiting on. I've got a massive backlog of new products that we want to bring out on ND. I have just been waiting for the right time to tackle them.

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