Comment · Tue, July 21, 2015
Closest RC or Pep to GH*?
Original post in this thread
arlowf · 2 points
Was wondering if you had anything coming, or any ideas on how to achieve, something similar to GHB that is legal?
I like G's health benefits, and getting "drunk" without the cals is the biggest benefit.
What they were answering
arlowf · 1 points
Oh, and phenibut is nothing like GHB and is horrible for your brain, in my experience.
u/MisterYouAreSoDumb
That's just the closest thing we would have. They both act on GABAb receptors. It's just GHB also acts as an agonist of the excitatory GHB receptor. Phenibut stimulates using a different mechanism.
GHB is horrible for your brain as well, since it decreases the expression of the NMDA receptors. It also causes a reduction in the number of neurons, and non-neuronal cells, in the CA1 region of the hippocampus and in the prefrontal cortex. It seems to cause oxidative stress as well. As far as I know, Phenibut is devoid of these neurotoxic effects.