Comment · Tue, January 13, 2015 · Ceretropic
Looking for a particular study on phenylpiracetam about its effect on neurotransmitters.
Original post in this thread
Ballaticianaire · 5 points
Topic. I'm looking for the study on phenylpiracetam that outlined its changes in neurotransmitter levels. I've tried google searching and on scholar and pubmed but I can't seem to find it anymore.
I'm sure someone here has it bookmarked or something, I've seen it on more than one occasion, so I'd appreciate someone posting it! Thanks in advance.
What they were answering
Ballaticianaire · 5 points
Nevermind guys I believe I finally found it here:
http://link.springer.com/article/10.1134/S1819712411020048
Interesting to say the least. I didn't realize the dosage was so massive in this study though. 100mg/kg? Lol. I usually wouldn't go above 100mg and I'm over 100kg and I feel quite a potent stimulant effect.
Yes, I realize the doses would have to be calculated to humans (which I don't feel like doing right now) but it's still massive. I guess this doesn't give quite as much insight as I thought into its neurotransmitter modulations.
It's too bad there's no mention of a noradrenergic interaction, that's one of the specifics I was looking for. However, it does seem to act as a typical racetam and modulate the glutamatergic and cholinergic systems slightly.
Also, interesting to see the bit on dopamine, which probably signifies some DA release via phenyl. That would explain its concentration boost in comparison to most other racetam agents.
Oh well, sorry about the thread guys, I guess I have my answer lol.
u/MisterYouAreSoDumb · Ceretropic
You have to realize that a lot of studies are using large dosages so they can observe a statistically significant effect in rats. That does not mean those can convert to the ideal dosage in humans. Ain't nobody taking 100 x 6 / 37 = 16mg/kg in humans. That would be me taking about 1.4g. That cray.