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Comment · Wed, September 4, 2013 · Ceretropic

Piracetam induces plasma membrane depolarization in rat brain synaptosomes.

What they were answering

bluecat1254 · 3 points

Out of curiosity, what is your opinion on considering racetams' modulating effects as a cause to pair them with NMDA receptor antagonists for those who are afraid of NMDA receptor downregulation (and the risks inherent in downregulation)?

u/MisterYouAreSoDumb · Ceretropic

I think it should be looked into more. I have a feeling that racetams have caused some NMDA down-regulation/tolerance in me personally. Memantine would be a good addition to a stimulant attack that contained racetams.

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