Comment · Wed, March 27, 2013
5-Methyl-MDA (infodump and request for experience reports) (x-post from /r/drugs)
Original post in this thread
SRnbomber · 8 points
There's not a lot of info out there on this drug, but I found a source for it, wanted to know more (like whether it's safe to use), and did what research I could. There's a very brief Wikipedia article, which gives a little bit of info, and a pretty-much-useless thread on Bluelight. It seems that about the only scholarly info on this compound is in this paper in the Journal of Medicinal Chemistry, which is paywalled (though I was able to access it through my university library proxy).
Here's a summary of the info I was able to glean from my searching:
Layman's info:
5MeMDA is an MDA derivative (duh) whose effects are supposed to include euphoria, empathogenic/entactogenic effects, and psychedelic effects; it is notably lacking in stimulant effects. It is also significantly more potent than MDA, with an active dose believed to be in the range of 15-25 mg (threshold dose likely around 5-10 mg).
More science-y stuff: (skip this if you don't care about how drugs work)
I say that the effects are supposed to include the above because I can't actually find a detailed, confirmed report of a human using it. The above in…
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb
I've never tried it, but much of MDMA's euphoria comes from it's NE and DA activity. Reducing the affinities for those systems is going to turn this molecule into more of an SSRI/5-HT releaser. Perhaps if combined with a mild DA/NE stimulant it might show good effects.
This guy says he had serious euphoria on it, but I would be skeptical of it, due to him being a vendor.
Could be interesting to try. I wouldn't personally, till more hard evidence is out.