Comment · Fri, December 21, 2012
Would micro-dosing MDMA on a daily basis be viable from a psychotherapy standpoint (anxiety, social lubrication, etc.) or does it's method of action and neurotoxicity prevent such use?
What they were answering
Toodlum · 2 points
Low doses of MDMA (<1mg) have been shown to up-regulate serotonin receptors which is probably the cause of this phenomena.
u/MisterYouAreSoDumb
Yes, like hypericin does. It would be interesting to know exactly why this happens, though. To my knowledge,nobody is sure what mechanism leads to the up-regulation.
Also, CYP2D6 inhibition may play a role as well.