Comment · Fri, November 16, 2012

I have a box full of drugs- not sure which to take at a show tonight. Need opinions.

Original post in this thread

[deleted] · 15 points

I'm going to an EDM show tonight and planned on taking LSD. However, my boyfriend and I have since gotten in a fight and are both thinking that taking a psychedelic isn't the best idea. We have MDMA but just took it a month ago and will be taking it again at a music festival in December so we didn't want to take it until the festival. We also have 5-meo-mipt, ketamine, ghb, 6-apb, 25i... And I think that's it. Only problem is we've only tried the 5-meo-mipt once and messed up the dosages so it wasn't a good time. We haven't had a chance to try the 6-apb or 25i yet. I'm wondering if it would be a bad idea to try the 6-apb for the first time at a show. Ketamine or ghb I feel wouldn't be very fun. Does anyone have ideas on combinations or doses to salvage tonight?

UPDATE: I quit being a pussy and ate acid with my boyfriend. It was a great time :) acid is nice

What they were answering

[deleted] · 1 points

Ahh we were under the impression 6-apb didn't affect MDMA tolerance. Thanks for the info!

u/MisterYouAreSoDumb

6-APB's monoamine re-uptake effects will have a cross-tolerance with MDMA, but it's psychedelic agonist effects will not. Down-regulation of your 5-HT receptors is going to happen either way, so there will be effects. I am not sure if 6-APB will lower tryptophan hyroxylase levels like MDMA. If it does, then it will take just as long to replenish your serotonin stores as taking MDMA.

Other MYASD lines in this thread

Comment · Fri, November 16, 2012 · 3 pts
Correct. The agonism of the 5-HT2 sub-receptor group is what gives traditional psychedelics, like LSD, their effects. MDMA's empathy and euphoria is caused by a release of monoamines, mainly serotonin. So if you were to

Related in the archive

Commentr/DrugsNov 8, 2012r/Nootropics years

Research Suggests no Neurotoxicity in MDMA

**I'm going to copy what I wrote on another thread:** _____________________________________________________ YES! Keep your damn body temperatures down people! http://www.maps.org/publications/1998_malberg_1.pdf http:

597PiracetamMagnesiumQuercetinDosing

Commentr/DrugsDec 19, 2012r/Nootropics years

Which substance, in your opinion, is the hardest to remember what happened afterwards? Also, what is your best blackout story?

Ativan (lorazepam) I was going to the Markus Schulz concert one night, here in Phoenix. At dinner, one of my friends rolls a pill across the table to me. He said it was an Ativan. I was like, ohh ok, thanks. I did not i

195

Postr/DrugsNov 22, 2012r/Nootropics years

MDMA Neurotoxicity Part 1 (Metabolites)

This is probably going to be the first in a series of discussions I start about MDMA. There's just too much information for one post. Therefore, I am going to start with one that is very interesting to me: MDMA's metabol

7776Quercetin

Commentr/DrugsApr 18, 2013r/Nootropics years

Experts: 5 Signs Your Teen Could Be Using Club Drug 'Molly' - This is one of the dumbest articles I've read in a long time.

>Molly is like the 70s version of crack Wait, what? I think they got their equivocation backwards, and their demographics mixed up. >but because the drug is so highly addicting, he said, "They're buying a lot of it."

Commentr/DrugsApr 9, 2013r/Nootropics years

How fucked am I r/drugs?

Don't ever admit anything to a police officer. EVER! The burden of proof is on them.

Commentr/DrugsApr 8, 2013r/Nootropics years

Man 'took 40,000 ecstasy tablets' - Doctors have revealed details of the biggest recorded user of ecstasy - a man estimated to have taken 40,000 ecstasy pills in his life.

Replying to Mentran · Why no redosing?

The metabolism characteristics of the drug mean that the first dose inhibits the main metabolic pathway, CYP2D6. This means that any subsequent doses are more likely to use the secondary metabolic pathway, CYP3A4. The CY

44Dosing