Comment · Fri, April 20, 2012
What's the worst drug experience you have had with someone?
Original post in this thread
bob_handerson · 1302 points
I was married to my first wife (I was 24, she was 32) and our life was pretty dull. I liked to smoke some weed once and awhile and thought it would be fun to do together. I nudged her for several years to try, but she always resisted.
Then on New Years Eve of 2002 she decided she would like to try. She didn't want to smoke, so I made a milky tea concoction. I did my best to get the proportions correct and give her a nice high. She also insisted that I don't get high until we see how it affects her.
She drank the tea and things were great for like 15 minutes. She was laughing and recalling funny stories. It was the most fun we had being married. She was totally relaxed and fun. And then BOOM. She starts freaking out and getting paranoid. She's crying and yelling at me "Why did you make me do this? I'm going to die!" This went on for about two or three hours. She was on the couch and she was convinced that if she got up she was going to fall and die. Which has fine, except later in the night she needed to poop. I told her she had to go to the bathroom but she would not budge. She said she would just poop on the couch. This night was already bad enough, I didn't want feces all ov…
What they were answering
no_username_needed · 1 points
What about stuff like harmaline? I was under the impression that so long as you avoided over-dosing with it, and ate carefully the day before, it would be fine.
Also, thanks a bunch for the information, I always love an opportunity to learn more about how my brain works.
u/MisterYouAreSoDumb
Harmaline is a monoamine oxidase A inhibitor as well as an acetylcholinesterase inhibitor. So it works on different mechanisms than the drugs I was talking about before. Keep in mind any monoamine oxidase inhibitor can cause dangerous issues when taken with other drugs. MAO-A and MAO-B are how your body breaks down used monamines. So inhibiting them causes an increase in the monoamines in your nervous system by slowing their breakdown. Take a releasing agent with these and you could have way too much of a certain monomaine in your system. Do not take harmaline with aged cheeses, beer, chocolate, coffee, etc. These foods are high in tyramine, and can cause hypertensive crisis when taken at the same time. Again, dosage is key with everything. Take just enough to get the desired effects!