Comment · Mon, August 28, 2023 · ND Owner

Isoliquiritigenin and heart health?

What they were answering

Direct reply to the original post in this thread.

u/MisterYouAreSoDumb · ND Owner

cAMP is necessary for your heart to function. It actually mediated the strength of cardiac muscle output. Low cAMP in cardiac muscle means weak heart function. This effect is actually good for the heart.

Isoliquiritigenin attenuates pathological cardiac hypertrophy via regulating AMPKα in vivo and in vitro

Isoliquiritigenin attenuates diabetic cardiomyopathy via inhibition of hyperglycemia-induced inflammatory response and oxidative stress

Natural Antioxidant-Isoliquiritigenin Ameliorates Contractile Dysfunction of Hypoxic Cardiomyocytes via AMPK Signaling Pathway

Isoliquiritigenin Inhibits Atherosclerosis by Blocking TRPC5 Channel Expression

Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats

It actually inhibits smooth muscles cells in the arteries, which is a mechanism behind atherosclerosis.

The inhibitory effect of Isoliquiritigenin on the proliferation of human arterial smooth muscle cell

These are all good things for the heart.

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