Micronisation

Lots of products on the market just claim to be micronized without it being true. Everyone just lies. Almost no brands have a particle size analyzing machine. Ours is really expensive, large, and loud. We had to build a sound absorbing shell for it, and keep it in a separate room in our lab, because it was hurting our lab tech's ears. This means almost zero brands have this equipment to analyze particle sizes on their QC batches. We even asked around to a lot of labs in the US, and most don't have the equipment to do it, either. So you can't really send off for the analysis, either. It's easier for brands just to put "micronized" on the label and hope nobody actually tries to verify it; because let's fact it, nobody but us will....

Now onto the question itself. Micronized only helps in a very small number of cases. If a product is water soluble, which most bioavailable things are, it makes zero difference. Where it does help is with poorly water soluble things. Bringing the particle size down can help to increase the surface area and give the non-soluble things more chance to come into contact with a mucous membrane in the GI tract. Even then, it only helps to a certain point. Take palmitoylethanolamide for example. We sell micronized, which means we control it for 50 microns or less. Most of the time the batches are in the 20 micron range. Then there is ultramicronized, which is 10 microns or less. However, studies have shown that micronized and ultramicronized performed the same for PEA, so it does help to get it under 50 microns, but doesn't further help to get it under 10 microns. If PEA was more water soluble, then it wouldn't even really be an advantage. It just happens that PEA is right in the limited solubility range where it does help to get it under 50 microns.