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Comment · Fri, June 3, 2022 · ND Owner

Enhancing nobiletin bioavailability

Original post in this thread

rokosbasilia · 7 points

Has anyone experimented with methods of increasing nobiletin bioavailability? I've seen in numerous papers discussions of low bioavailability and suggestions to enhance uptake- has anyone tried anything with concrete feedback? I.e., bioperine, astrragin, cyclodextrin? BTW, this is absolutely my favorite product, and the published science on this stuff is breathtaking!

What they were answering

callitblues · 2 points

It's such a wonderful compound. IDK why ND didn't make it with cyclodextrin or something like that. /u/misteryouaresodumb

edit- I wonder why not just slump some cyclodextrin or other methods to straight up improve the bioavailability of all the these 0.5% absorption compounds. I've read some papers and it seems to be quite simple in lab settings.

u/MisterYouAreSoDumb · ND Owner

We have considered doing some cyclodextrin encasing ourselves in the lab. Scaling up to production sizes might be an issue, though. Simple things at lab scale can get complicated quickly at production scale.

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