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Comment · Wed, June 9, 2021 · ND Owner

N-acetyl-l-tyrosine ineffective

Original post in this thread

Nocasual · 14 points

To my knowledge n-acetyl-l-tyrosine was shown in studies to be ineffective in raising tyrosine levels in the brain whereas L-tyrosine was much more effective. My question is why does ND carry a seemingly ineffective product? Is there something I am missing?

What they were answering

sirsadalot · 3 points

I knew it! Yeah, I've been rewiring my brain now for a while after I started picking up on how many false narratives there truly are floating around on reddit. It doesn't make sense that an acetylated amino acid would have no effect on the brain if a large portion was excreted in urine.

You say NALT may bind to a receptor. What receptor would that be? And maybe you can use your massive influence to update wikipedia, examine, or selfhacked, because the information they had up on there was completely useless.

u/MisterYouAreSoDumb · ND Owner

We can only speculate, but there have been some modified versions of NALT created that bind to PPARα. They have also discovered that L-tyrosine and L-DOPA have their own receptors in the body they can bind to and act as hormone-like compounds in the body.

https://onlinelibrary.wiley.com/doi/full/10.1111/j.1755-148X.2011.00898.x

https://sci-hub.do/10.1016/0303-7207%2894%2990001-9

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