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Comment · Sat, March 27, 2021 · ND Owner

How Long Do the Effects of Sabroxy Last?

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tfgust · 3 points

The title says it all. I can't find any decent info on how long Sabroxy lasts easily available online. Is it a 2-3 hour thing, or a 10 hour thing, or is it going to keep you up at night for the next 72 hours? Thank you!

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tfgust · 5 points

Yeah, doses, right! I take kanna all of the time, it is likely my #1 supplement and nootropic, but I only need 25mg of extract to feel it. Other people need 250mg of the same extract to feel anything at all. Pretty insane, especially when you factor in that kanna has extremely dose-dependent effects. People frequently take too much kanna and then complain about the anxiety and headaches it causes- lol. Or they take too little, and say "it doesn't do much" because they didn't realize they need to literally take 10x the normally recommended dose.

Wish you guys would stock a high-mesembrine kanna extract.

Not Zembrin, Zembrin is crappy, expensive, and their extract attempts to reduce the amount of mesembrine and increase the amount of mesembrenone (which is much weaker than mesembrine and lacks the potent VMAT2 upregulation that mesembrine causes). That VMAT2 upregulation is the key to the neuroprotective, empathogenic, addiction-suppressing, mood-boosting, and stimulant effects. Sure, mesembrine can cause some anxiety for a few people, but the other effects make kanna worth it. No other drug upregulates VMAT2 the way kanna does.

I wish there were better standardized high-mesembrine kanna extracts. Liftmode's extract, likely the best high-mesembrine product on the US market right now, is standardized to >3% mesembrine, but in reality, their alkaloid levels are all ove…

u/MisterYouAreSoDumb · ND Owner

We are already working on a good kanna extract. Our bank was not cool with it for a while, but we convinced them to allow us. We certainly will do a more controlled extract. The other issue is that South Africa was/is hit hard by COVID, so suppliers there are very hard to get a hold of right now. All the "kanna" we have gotten from China has been fake. All of it. So South Africa and a couple other countries in southern Africa are the best place, but they are not the most reliable at the moment.

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