Comment · Fri, February 26, 2021 · ND Owner
Oroxylin-A First Impressions (Sabroxy)
Original post in this thread
sirsadalot · 88 points
Disclaimer: N = 1 and first day review, so take this with a grain of salt. I'm only making this review because dopamine reuptake inhibitors are very noticeable, so placebo is less of an issue.
This stuff is STRONG. Much more than I had anticipated, and certainly more than most nootropics.
Comparison: It feels like other stimulants, but I'd like to correct my comparison of it to caffeine: it is much less anxiogenic. It's stronger than Adrafinil (200mg). Less euphoric and more wakeful than Phenylpiracetam (100mg).
Anxiety: My heart isn't racing. I'm not jolty. Yet the stimulation is very noticeable. Assertiveness is up, as is impulsivity. I feel more awake, and maybe better at processing things. Probably still not good for generalized anxiety, however, because some of these indicate higher noradrenaline.
Dose: My dose was 200-250mg. MYASD suggests 100mg. It depends on the person I guess. I don't mind this dose and I may consider replacing caffeine with it temporarily.
Time: It's been around 4 hours since my initial dose, and it seemed to have an onset of 45 minutes to an hour. MYASD claims stimulation should persist for 4 additional hours. I'll update this post when I get ther…
What they were answering
humanbeingbeing · 3 points
Ive tried this twice now, first 150mg - didn’t notice much but I would get moments of dopamine stimulation 2-3 hrs after taking, second day took 400mg, again unfortunately not terribly noticeable but I did feel slightly more focused, and would get more of the stimulation flashes- I think I notice a slight appetite suppressant effect, I was disinterested in eating all day and got a decent amount of coding done so it could be working- very subtle tho, gonna try 500mg tomorrow
u/MisterYouAreSoDumb · ND Owner
Remember, Sabroxy is mostly hitting DA without any NE. Most people who like the "pushy" stimulation from certain things are really liking the interplay between the increased dopamine AND norepinephrine. Sabroxy won't give that. It is hitting DA alone. For those with attention issues that can be good, because it calms them down and lets them focus. However, it won't be a pushy stim feeling without adding something else in there to hit NE.