Comment · Tue, October 20, 2020 · ND Owner
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Original post in this thread
NootropicsDepotCom · 28 points
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What they were answering
Malician · 6 points
The first study seems a bit negative:
"The results of this study indicate no benefit of (–)-epicatechin supplementation at 200 mg per day in conjunction with cycling. Additionally, (–)-epicatechin appeared to inhibit adaptations in relative peak aerobic power and skeletal muscle SDH protein content, compared with the placebo. In conclusion, chronic (–)-epicatechin supplementation combined with exercise training in healthy adults may be disadvantageous."
u/MisterYouAreSoDumb · ND Owner
Yeah, the first study was a bit of a letdown. It still discussed the mechanisms.
https://www.nmd-journal.com/article/S0960-8966(15)00637-9/abstract
https://www.pnas.org/content/103/4/1024.short
https://academic.oup.com/ajcn/article/98/4/861/4577158
https://www.sciencedirect.com/science/article/abs/pii/S0006291X07012077
https://www.ahajournals.org/doi/full/10.1161/hypertensionaha.109.147892
https://www.sciencedirect.com/science/article/abs/pii/S0006291X05008132
https://www.sciencedirect.com/science/article/abs/pii/S0006295219303983
https://www.sciencedirect.com/science/article/abs/pii/S0955286313002076