Comment · Tue, September 8, 2020 · ND Owner
A Question about the Theacrine (Teacrine) Blog Post
Original post in this thread
Berengersbottle · 2 points
I love theacrine for its mood-boosting properties. My motivation to exercise skyrockets, my outlook on life dramatically brightens, and my libido even pops up a couple levels. The only issue is that I feel like it actually decreases my cognitive performance. It's not a dramatic drop, but I do find myself making more errors in my work. I think it may have to do with an enhanced sense of confidence, but I'm not sure.
My question about the blog post is related to the above mentioned anecdotal effects. The ND blog (as well as many others) mentions that theacrine "activates dopamine receptors." What exactly does this mean? In the case of other substances, they might increase dopamine levels by blocking the transporter, inhibiting reuptake, perhaps acting as an agonist, or in more indirect ways such as nicotine's MOA.
I ask because I wonder if there's something I might stack with theacrine to modulate the cognitive effects, so that I still get the mood-lifting effects while eliminating the proclivity to pass over easy mistakes.
Thanks in advance.
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · ND Owner
So the adenosine and dopamine receptors are linked. Theacrine helps to activate the DA receptors by modulating the adenosine receptors. It is not directly binding to the DA receptors, though. It's due to the coupling of the adenosine and dopamine systems.