Comment · Tue, June 23, 2020 · ND Owner

Why Would Otim-ALA Make Me Depressed?

Original post in this thread

Experienced8 · 7 points

Long story short, I isolated Natrium Health's Optim-ALA as the supplement making me depressed.

I've tried taking it 30 minutes before a meal and with food, everytime it makes me depressed, tired, slight headache, and very unmotived.

Does anyone have a guess as to why this would happen? I really want to figure out my underlying problems.

I'm not knocking Natrium Health or Nootropics depot either. They are the BEST.

What they were answering

Experienced8 · 1 points

The last few days I stopped taking everything besides the Optim-ALA and still was having these issues... but normally I've also been taking magnesium glycinate, berberine, CoQ10,b12, Injuv, and White Jelly Mushroom from ND.

u/MisterYouAreSoDumb · ND Owner

Ahh, that's probably it! It's the rapid cessation of the CoQ10 and berberine. I get rebound mood issues ceasing those two. Berberine has a lot more mood effects than most people realize.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307759/

https://pubmed.ncbi.nlm.nih.gov/26773864/

I would try the OptimALA with your normal stack and see if that has the same effects.

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